A young New York City nurse who spent her nights caring for others was killed in a heartbreaking hit-and-run just minutes after finishing her shift — and the driver who struck her is still on the loose.

Jiayi Zheng, 28, had just wrapped up an overnight shift at NYU Langone Hospital—Brooklyn when she started walking home Saturday morning, Aug. 29.

She never made it.

Police said Zheng was crossing Third Avenue at 55th Street in Brooklyn’s Sunset Park neighborhood at about 7:30 a.m. when a Cadillac sedan slammed into her.

The impact was so violent that Zheng was thrown into the roadway, leaving her with severe injuries to her head and body.

Surveillance footage viewed by local news outlets reportedly shows Zheng wearing hospital scrubs and carrying a backpack as she waits for the traffic signal before entering the crosswalk.

She made it about halfway across the street when the Cadillac came speeding into the intersection and struck her without appearing to slow down.

The driver then continued south on Third Avenue and fled the scene, according to reports.

In a devastating twist, emergency crews rushed Zheng to NYU Langone Hospital—Brooklyn — the same hospital where she worked as a nurse.

Doctors there were unable to save her, and she was pronounced dead.

Zheng reportedly lived less than a mile from the crash site and roughly a mile from the hospital. She had been heading home after spending the night caring for patients.

New York State Sen. Andrew Gounardes confirmed her death on social media.

“The victim, a nurse coming off the night shift, has passed from her injuries,” he wrote. “Please keep her in your prayers.”

Coworkers remembered Zheng as a cheerful and dedicated nurse who worked in the hospital’s medical-surgical unit.

Hospital sources told News12 she was “always positive and in a good mood.”

NYU Langone spokesperson James Iorio said the hospital community had been shaken by her sudden death.

“We are deeply saddened by the passing of Jiayi Zheng, a nurse at NYU Langone Hospital—Brooklyn,” Iorio said. “This is a tragic loss, and we extend our sincere condolences to her family, loved ones, and colleagues.”

He added that nurses play an essential role caring for patients “with compassion and dedication” and said Zheng’s death was being felt throughout the hospital community.

A worker at nearby Mendez Deli described the disturbing moments after the crash.

The employee told the New York Daily News that customers alerted the store to an accident outside, and someone quickly called 911 after seeing Zheng lying in the street.

“I feel so bad,” the worker told the outlet. “I couldn’t handle seeing that. It was very bad.”

Police have identified the vehicle involved as a 2014 Cadillac sedan.

But the person who was behind the wheel has not been publicly identified.

No arrests had been made as authorities continued searching for the driver.

The NYPD Highway District’s Collision Investigation Squad is investigating the deadly crash.